SS-31

10mg

SS-31 (elamipretide, also referenced as MTP-131) is a synthetic aromatic-cationic tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2, where Dmt is 2',6'-dimethyltyrosine. The alternating cationic and aromatic residues give the molecule a net positive charge at physiological pH while remaining membrane-permeant, and it is this combination that underlies its defining property: selective association with cardiolipin, the signature phospholipid of the inner mitochondrial membrane. Research has focused on how that interaction affects cristae curvature, the assembly of electron transport chain supercomplexes, and electron leak at complexes I and III. Because the peptide targets a structural lipid rather than a receptor, it is investigated across a wide range of mitochondrial bioenergetics models, including primary mitochondrial myopathy, cardiolipin remodelling disorders and ischaemia-reperfusion. Supplied as lyophilised powder.

Published research on SS-31 is indexed on PubMed.

Intended Use: Strictly for in-vitro laboratory research. Not for use in humans or animals. Not to be used in foods, drugs, or medical diagnostics. This product has not been evaluated by the MHRA or FDA. Buyer assumes full responsibility for safe handling and regulatory compliance.