Growth Hormone Secretagogues

CJC-1295 + Ipamorelin

Name: CJC-1295 + Ipamorelin 5+5mg
Brand: UK Peptide Lab
SKU: UKPL-400
Price: 42.99 GBP
Availability: InStock

5+5mg

Pre-blended GHRH + GHRP research peptide vial. CJC-1295 (no DAC) and Ipamorelin combined.

£42.99In Stock

Content-verified · Third-party tested · Batch UKPL-564 · View certificate

Size

5+5mg£42.99 10+10mg£59.99

Quantity

Same-day dispatch before 3pm, Mon to Fri
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Research use only. For in-vitro laboratory research. Not for use in humans or animals, or in food, drugs or diagnostics. Not evaluated by the MHRA or FDA. The buyer is responsible for handling and regulatory compliance.

Bulk Pricing

Counted across your basket, any mix of products.

Vials in basket	Discount	Per vial
1	None	£42.99
3-4	5%	£40.84save £2.15
5-9	8%	£39.55save £3.44
10-50	12%	£37.83save £5.16

Don't Forget

Bacteriostatic Water 10ml

Required to reconstitute lyophilised peptides.

£4.99

What is CJC-1295 + Ipamorelin?

CJC-1295 + Ipamorelin 5+5mg is one vial holding 5mg of CJC-1295 without DAC and 5mg of ipamorelin, lyophilised together. Also written CJC1295/ipamorelin, it pairs a GHRH analogue with a selective ghrelin-receptor agonist.

Full description

CJC-1295 without DAC, or modified GRF (1-29), is a 29 amino acid GHRH analogue with four substitutions: D-Ala2, Gln8, Ala15 and Leu27. It acts at the GHRH receptor. Ipamorelin is the pentapeptide Aib-His-D-2-Nal-D-Phe-Lys-NH₂, a selective agonist at the ghrelin receptor, GHS-R1a. Both receptors sit on the pituitary somatotroph.

Equal mass is not equal moles. At 3367.9 and 711.85 g/mol, the vial holds about 1.5 µmol of CJC-1295 and 7.0 µmol of ipamorelin, roughly 1 to 4.7.

CJC-1295 + Ipamorelin Research Applications

Typical preclinical uses are dual-receptor somatotroph stimulation and pulsatile GH release studies with both inputs applied together. The fixed ratio removes one source of preparation error across a replicate series.

CJC-1295 + Ipamorelin vs the Components Alone

The blend gives both peptides from one vial, one reconstitution and one certificate, at a fixed 1:1 mass ratio. That suits designs that apply both inputs together. The ratio cannot change once the powder is dissolved. A single-agent control arm, independent concentrations or attribution to one receptor need the separate CJC-1295 and ipamorelin vials. No controlled study of this specific blend has been published, so the evidence comes from each peptide's own literature.

Research Overview

This is a single vial containing two distinct growth hormone secretagogues, CJC-1295 without DAC and Ipamorelin, supplied pre-blended at 5mg of each. The two act on separate receptors, which is the entire reason they are studied together rather than as alternatives to one another.

CJC-1295 without DAC is more precisely described as tetrasubstituted GRF(1-29), a 29-amino-acid fragment of growth hormone releasing hormone carrying four substitutions (D-Ala at position 2, Gln at 8, Ala at 15 and Leu at 27). The substitution at position 2 is the functionally important one: it blocks cleavage by dipeptidyl peptidase-4, the protease that degrades native GRF within minutes. It binds the GHRH receptor on the pituitary somatotroph and signals through the cAMP/PKA pathway. Because it lacks the drug affinity complex, it does not covalently bind serum albumin and its action remains short, which is precisely what makes it useful for studying pulse shape rather than sustained elevation.

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that acts at a completely different target, the ghrelin receptor GHS-R1a. Raun and colleagues (Eur J Endocrinol, 1998) characterised it as the first growth hormone releasing peptide with selectivity approaching that of GHRH itself, reporting growth hormone release without the accompanying ACTH and cortisol elevation seen with earlier compounds in the class such as GHRP-6 and hexarelin. That selectivity is the single most cited property of the molecule.

Pairing a GHRH analogue with a GHS-R1a agonist is a long-standing design in secretagogue research, following the work of Bowers and colleagues showing that the two classes produce a greater combined response than either alone. The usual mechanistic explanation is that the GHRH arm drives somatotroph cAMP signalling while the GHRP arm additionally attenuates somatostatin tone, so the two are acting on different limbs of the same axis rather than competing for one receptor.

Product Specifications

CJC-1295 + Ipamorelin · Technical Data

Components: CJC-1295 (no DAC) 5mg + Ipamorelin 5mg
CJC-1295 (no DAC) CAS: 863288-34-0
CJC-1295 (no DAC) Molecular Weight: 3367.9 g/mol
Ipamorelin CAS: 170851-70-4
Ipamorelin Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Ipamorelin Molecular Weight: 711.85 g/mol
Identity: Both components confirmed against reference standards
Purity: >99% blend purity (RP-HPLC)
Form: White lyophilised powder (single vial)

Certificate of Analysis

Third-party tested

Batch: UKPL-564
Purity: >99%
Method: RP-HPLC
Lab: Marfleet Analytical Services Ltd
Tested: Aug 2026

View Lab Certificate Verify batch UKPL-564

Need the certificate for an earlier batch? Request an older CoA

Storage and Reconstitution

Store the sealed vial at -20°C, away from light and moisture, for up to 24 months. After reconstitution, keep the solution at 2-8°C and use it within 4 weeks, or freeze single-use aliquots at -20°C. Both peptides share one reconstitution date, so aliquot at the start.

Vials are sold on their own, without bacteriostatic water for mixing or other supplies.

How to reconstitute and handle

Treat the vial as one 10mg preparation, with the fill volume set by the concentration your design needs. Let the vial and the bacteriostatic water reach room temperature and swab both stoppers with alcohol. Add the water slowly down the inside wall of the vial and swirl gently until dissolved. Do not shake or vortex. The solution should be clear and colourless.

Both components are in the same vial and go into solution together, so the blend cannot be separated after reconstitution. Study designs needing the two compounds at independent concentrations should use the separate CJC-1295 and Ipamorelin vials instead.
Work under aseptic conditions with sterile syringes and alcohol-swabbed stoppers. Avoid repeated freeze-thaw cycles and aliquot reconstituted stock for reproducibility.

For the full method, see the peptide reconstitution guide and the reconstitution calculator.

Research References

Published research on CJC-1295 + Ipamorelin is indexed on PubMed. See our full UK buyer's guide for Ipamorelin, UK buyer's guide for CJC-1295 and UK buyer's guide for CJC-1295 Ipamorelin.

CJC-1295 + Ipamorelin Price (UK)

CJC-1295 + Ipamorelin is for sale in 2 vial sizes, priced from £42.99 for 5+5mg to £59.99 for 10+10mg. Every size ships from our UK facility, each with its own batch certificate. UK delivery is £4.50 by Royal Mail Tracked 24, free over £69.

CJC-1295 + Ipamorelin · Price per vial

Vial	Price	Cost per mg	Availability
CJC-1295 + Ipamorelin 5+5mgThis page	£42.99	£4.30	In stock
CJC-1295 + Ipamorelin 10+10mg	£59.99	£3.00Best value	In stock

Prices are in GBP per vial and match the basket. See the FAQ for delivery and payment options, and quality & testing for how each batch is checked.

Frequently Asked Questions

What is CJC-1295?

CJC-1295 here means CJC-1295 without DAC, also written tetrasubstituted GRF(1-29): a 29-amino-acid analogue of growth hormone releasing hormone. This product pairs it with Ipamorelin in one vial for laboratory research. The single-compound vial is on the CJC-1295 product page. Research use only.

What is in a CJC-1295 and Ipamorelin blend vial?

One vial containing 5mg of CJC-1295 without DAC and 5mg of Ipamorelin, 10mg of peptide in total, lyophilised together. Batch UKPL-564 is verified at ≥98% per component by HPLC and the certificate is published on this page.

Why are CJC-1295 and Ipamorelin studied together?

They act at two different receptors. CJC-1295 without DAC is a GHRH analogue binding the GHRH receptor on pituitary somatotrophs, while Ipamorelin is a selective agonist at the ghrelin receptor GHS-R1a. Because the targets are distinct rather than overlapping, combination designs following Bowers and colleagues report a greater response than either class produces alone, generally attributed to the GHRP arm additionally reducing somatostatin tone.

What is the difference between CJC-1295 with and without DAC?

The drug affinity complex is a maleimide group that binds covalently to serum albumin, extending the molecule's presence in circulation from minutes to days. CJC-1295 without DAC, the version in this blend, has no such group, so its action is short and pulse-shaped. The DAC version is stocked separately for study designs where sustained exposure is the variable of interest.

Is Ipamorelin selective?

Selectivity is Ipamorelin's defining characteristic in the literature. Raun and colleagues (Eur J Endocrinol, 1998) reported growth hormone release without the ACTH and cortisol elevation that accompanies earlier growth hormone releasing peptides such as GHRP-6 and hexarelin, describing selectivity comparable to GHRH itself. That cleaner profile is why it is the compound most often chosen for combination work.

Should I buy the blend or separate vials?

The blend is the lower cost per milligram and the simpler option when both compounds are wanted at a fixed 1:1 ratio. Because both go into solution together, the ratio cannot be changed after reconstitution, so any design needing the two at independent concentrations requires the separate CJC-1295 and Ipamorelin vials, which we also stock.

Where can I buy CJC-1295 and Ipamorelin blend in the UK?

You can buy the CJC-1295 + Ipamorelin 5+5mg blend online from UK Peptide Lab, shipped from UK stock. A 10+10mg vial is also for sale. Orders placed before 3pm (UK time) on a working day are dispatched the same day, and UK delivery is free over £69.

Is your CJC-1295 Ipamorelin blend third-party tested?

Yes. Marfleet Analytical Services tested batch UKPL-564 by RP-HPLC. It confirmed the identity of both CJC-1295 (no DAC) and ipamorelin against reference standards, and measured blend purity above 99% against a 98.0% specification.

Should I buy the blend or the individual CJC-1295 and Ipamorelin vials?

Buy the blend for both peptides at a fixed 1:1 mass ratio from one vial. Buy the individual 5mg vials to vary the ratio, run a single-agent control or attribute an effect to one receptor. Each format has its own batch and certificate.

Research Use Disclaimer