Ipamorelin
10mg
Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) with selective agonist activity at the ghrelin receptor. Research has examined its growth hormone secretagogue activity and its selectivity profile relative to other GHRP-class peptides. This 10mg presentation is the higher-mass research format of our 5mg vial. Supplied as lyophilised powder, supplier-tested, with the certificate published on this page and independent third-party verification pending.
Published research on Ipamorelin is indexed on PubMed.
Intended Use: Strictly for in-vitro laboratory research. Not for use in humans or animals. Not to be used in foods, drugs, or medical diagnostics. This product has not been evaluated by the MHRA or FDA. Buyer assumes full responsibility for safe handling and regulatory compliance.
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Bacteriostatic Water 10ml
Required to reconstitute lyophilised peptides.
Research Use Only
This product is intended strictly for research and laboratory use only. Not for human consumption, medical use, or diagnostic purposes.
Certificate of Analysis
Third-party tested
Lyophilised Stability
24 months
Sealed at -20°C, light-protected
Reconstituted Stability
Up to 3 months
Stored at 2-8°C after mixing
Cold-Chain Shipping
Always
Dry-cold pack, Royal Mail Tracked 24
Important Notice
All compounds are sold individually and do not include research supplies. Products are provided in lyophilised (powder) form and require proper reconstitution before use in research settings.
Related Products
Ipamorelin Price (UK)
Ipamorelin is supplied in 2 vial sizes, priced from £21.99 for 5mg to £29.99 for 10mg. Every size ships from our UK facility with the same third-party HPLC certificate published on this page. UK delivery is £4.50 by Royal Mail Tracked 24, or free once your basket reaches £45 (£15.01 away at this price). Orders placed before 2pm on a working day are dispatched the same day.
| Vial | Price | Cost per mg | Availability |
|---|---|---|---|
| Ipamorelin 5mg | £21.99 | £4.40 | In stock |
| Ipamorelin 10mgThis page | £29.99 | £3.00Best value | In stock |
Prices are in GBP and shown per vial as supplied, lyophilised, for in-vitro laboratory research only. Cost per mg is given so researchers can compare vial sizes on a like-for-like basis. Stock and pricing on this table are read live from our inventory, so they match the basket. See our FAQ for delivery and payment options, and quality & testing for how each batch is verified.
Product Specifications
Research Overview
This page covers the 10mg presentation. The compound is the same synthetic pentapeptide supplied in the standard vial, sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂, molecular weight 711.85 g/mol, CAS 170851-70-4, a selective agonist at the ghrelin receptor GHS-R1a. Its characterisation by Raun and colleagues (Eur J Endocrinol, 1998) as the first selective growth hormone secretagogue, and the receptor context established by Howard and colleagues (Science, 1996) and Kojima and colleagues (Nature, 1999), are documented in full on the main Ipamorelin page. What is specific to the 10mg vial is handling and economics.
Ten milligrams is twice the content of the 5mg vial in the same single-vial glass format, so at a fixed fill volume the reconstituted stock is twice as concentrated. Fill volume must therefore be scaled to the target concentration rather than carried over from smaller-vial work, and the resulting concentration recorded against the batch. Unlike methionine-bearing peptides in the secretagogue class, ipamorelin carries no methionine, no cysteine and no tryptophan, and its D-amino acid and aminoisobutyric acid residues give the molecule marked stability in solution, so oxidative exposure is not the governing constraint on a larger vial. The constraints that do grow with vial size are microbial and mechanical: a vial holding twice the mass is typically accessed over a longer period and across more stopper penetrations, so sterility discipline and aliquoting into single-use volumes matter more here than on a 5mg vial.
The offsetting advantages are batch continuity under one certificate of analysis and a lower cost per milligram, since vial, stopper, lyophilisation and assay costs are incurred per vial rather than per milligram. Each vial contains 10mg of ipamorelin as white lyophilised powder, batch UKPL-9516, supplier-tested at 99.61% purity by HPLC, with the supplier certificate of analysis published on this page and independent third-party verification pending. Supplied strictly for in-vitro laboratory research use only.
Product Specifications
Laboratory Handling
- Scale the bacteriostatic water fill volume to your target concentration. A 10mg vial reaches twice the concentration of a 5mg vial at the same fill volume, so a volume carried across from smaller-vial work will not reproduce the same stock.
- The sequence contains no methionine, cysteine or tryptophan, and the D-amino acid and aminoisobutyric acid residues make ipamorelin comparatively resilient in solution, so no oxidation-specific handling is required. Sterility is the limiting factor.
- Aliquot into single-use volumes immediately after reconstitution and hold them at -20°C. A 10mg vial means a longer in-use window and more accumulated stopper penetrations on a single stock, and aliquoting isolates each withdrawal from that history.
- Introduce the diluent slowly down the inner glass wall, never onto the lyophilised cake, and swirl gently until fully dissolved. Never shake or vortex. Allow the vial to reach room temperature before opening.
- Do not leave dilute solution standing at room temperature. Return aliquots to cold storage promptly after each withdrawal rather than working from a stock left out across a session, and avoid repeated freeze-thaw cycles.
Frequently Asked Questions
What is Ipamorelin?
The 10mg vial is the higher-mass presentation of ipamorelin, the synthetic pentapeptide growth hormone secretagogue with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂, molecular weight 711.85 g/mol, CAS 170851-70-4. It holds twice the lyophilised mass of the 5mg vial in the same single-vial glass format, and the compound in both is identical. The full chemistry, the characterisation by Raun and colleagues (Eur J Endocrinol, 1998) as the first selective growth hormone secretagogue, the GHS-R1a receptor context and the discontinued clinical programme are documented on the main Ipamorelin page and are not repeated here. This page documents what is specific to the 10mg format: the twofold concentration reached at a fixed fill volume, why oxidative exposure is not the governing constraint for this sequence, and where the larger vial is the better use of budget. Supplied as lyophilised powder for in-vitro research use only.
The 10mg Vial vs the 5mg Vial: Content, Cost and Working Life
Both vials hold the same peptide, so the comparison is entirely about logistics rather than pharmacology. At a fixed fill volume the 10mg vial reaches twice the concentration of the 5mg, so reconstitution volumes must be scaled from the concentration your protocol specifies rather than carried over from smaller-vial work. Cost per milligram falls with vial size, because the vial, stopper, lyophilisation cycle and assay costs are incurred per vial rather than per milligram. Batch continuity is the other argument: one batch under one certificate of analysis covers twice as much work, and a long design run against a single batch removes inter-batch variance from the analysis. The usual objection to larger vials, cumulative oxidative exposure over a longer in-use window, applies far less here than to methionine-bearing secretagogues, because ipamorelin contains no methionine, no cysteine and no tryptophan, and its D-amino acid and aminoisobutyric acid residues make the stored solution comparatively resilient. The constraints that do grow with vial size are microbial and mechanical, more stopper penetrations and a longer working life on one reconstituted stock, and aliquoting into single-use volumes at the point of reconstitution addresses them.
Ipamorelin Research Applications
The applications are those documented for the main Ipamorelin page, since the compound is the same: GHS-R1a receptor pharmacology with ipamorelin as the selective agonist control, binding and functional cAMP or calcium-mobilisation assays in receptor-transfected cell lines, pulsatile GH release kinetics, bone metabolism work following the Johansen rat studies, and two-receptor designs pairing it with GHRH-receptor agonists such as CJC-1295. Vial content matters to study logistics rather than to endpoint selection. Dose-response matrices across many wells or plates, repeated agonist controls in long time-course designs and analytical method development all consume material faster than a 5mg vial supports comfortably, and running the whole design against one 10mg batch keeps a single purity figure and a single certificate behind the entire dataset.
Reconstitution Guide
Allow the vial and the bacteriostatic water to reach room temperature, then swab both rubber stoppers with alcohol. Inject the diluent slowly down the inner glass wall rather than onto the lyophilised cake, and swirl gently until fully dissolved. Never shake or vortex. The solution should be clear and colourless. Two points are specific to the 10mg vial. First, fill volume must be set from your target concentration: 10mg in 2mL gives a 5mg/mL stock, and the same 10mg in 1mL gives 10mg/mL. We specify no fill volume, as that is a protocol decision, and provide no dosing information. Second, ipamorelin is a short, robust pentapeptide with no methionine, cysteine or tryptophan, so handling is forgiving by peptide standards and aseptic technique, not oxidation, is the limiting factor. Label the vial with the reconstitution date and refrigerate immediately.
See our full peptide reconstitution guide and reconstitution calculator for step-by-step protocol.
Storage Instructions
Lyophilised vials should be stored at -20°C, protected from light and moisture, and remain stable for up to 24 months. Once reconstituted, hold the solution at 2-8°C and use within approximately 4 weeks, preparing single-use aliquots at -20°C for anything longer. Because the sequence carries no oxidation-prone residues, the practical failure modes on a larger vial are repeated stopper penetrations and freeze-thaw cycling of a single long-lived stock rather than air exposure, so aliquot at reconstitution and re-enter each aliquot once. Handle under sterile laboratory conditions throughout.
Frequently Asked Questions
Research References
Ipamorelin
10mg · £29.99